Catalogue number: C427750
Chemical name: (Z)-2-(4-Chlorophenyl)-5-(4-methoxybenzylidene)-5H-thiazol-4-one
Synonyms: (5Z)-2-(4-chlorophenyl)-5-[(4-methoxyphenyl)methylene]-4(5H)-thiazolone; CAY10649;
CAS Number: 1272519-89-7
Possible CAS #: NA
Molecular form.: C₁₇H₁₂ClNO₂S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 329.8
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: A novel class of potent direct 5-lipoxygenase (5-LO) inhibitors bearing a thiazolinone-scaffold. These disubstituted thiazolinones may possess potential for intervention with inflammatory and allergic diseases and certain cancer types. Anti-inflammatory agent.
Dangerous Goods Info: NA
References: Werz, O., et al.: Pharmacol. Ther., 112, 701 (2006), Franke, L., et al.: J. Med. Chem., 50, 2640 (2007), Hofmann, B., et al.: ChemMedChem., 3, 1535 (2008), Menna, C., et al.: Curr. Pharm. Des., 16, 725 (2010),
Peer Review Product Citations:

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