Chloro Sofosbuvir

Catalogue number: C382095
Chemical name: Chloro Sofosbuvir
Synonyms: N-[[P(S),2’R]-2’-Chloro-2’-deoxy-2’-methyl-P-phenyl-5’-uridylyl]-L-alanine 1-Methylethyl Ester
CAS Number: 1496552-51-2
Possible CAS #: NA
Molecular form.: C₂₂H₂₉ClN₃O₉P
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 545.91
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Phosphorylating and Phosphitylating Agents
Boiling Point: No Data Available
Applications: Chloro Sofosbuvir is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2’-deoxy-2’-α-fluoro-β-C-methyluridine-5’-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Dangerous Goods Info: NA
References: Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010)
Peer Review Product Citations:

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  Pack size Price(USD)
.5mg $200.00
  Pack size Price(USD)
5mg $1600.00
Exact Weight Packaging ($75(USD) / Vial)
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