4-[4-(3-Chloropropyl)-1-piperazinyl]-2-(1,1-dimethylethyl)-6-(trifluoromethyl)pyrimidine

Catalogue number: C381215
Chemical name: 4-[4-(3-Chloropropyl)-1-piperazinyl]-2-(1,1-dimethylethyl)-6-(trifluoromethyl)pyrimidine
Synonyms: 2-tert-Butyl-4-[4-(3-chloropropyl)piperazin-1-yl]-6-(trifluoromethyl)pyrimidine
CAS Number: 219600-00-7
Possible CAS #: NA
Molecular form.: C₁₆H₂₄ClF₃N₄
Appearance: Pale Yellow Solid
Melting Point: No Data Available
Mol. Weight: 364.84
Storage: No Data Available
Solubility: Chloroform, DCM
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: 4-[4-(3-Chloropropyl)-1-piperazinyl]-2-(1,1-dimethylethyl)-6-(trifluoromethyl)pyrimidine is an intermediate in the synthesis of ABT 925 Fumerate (A112600) is a dopamine D3 receptor antagonist that is used in the treatment of acute schizophrenia. 4-[4-(3-Chloropropyl)-1-piperazinyl]-2-(1,1-dimethylethyl)-6-(trifluoromethyl)pyrimidine is also used in the preparation of of other dopamine D3 receptor modulators such as 1-(4-pyrimidinyl)piperazines and pyrimidin-2-ones, that are used to treat central nervous system disorders.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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