Catalogue number: C380747
Chemical name: N-(5-Chloropyridin-2-yl)-N’-[(1S,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide-d6
Synonyms: Edoxaban Impurity H-d6; 2,4-diepi-Edoxaban-d6; (2S,4R)-Edoxaban-d6;
CAS Number: NA
Possible CAS #: unlabelled:1255529-28-2
Molecular form.: C₂₄H₂₄D₆ClN₇O₄S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 554.09
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: N-(5-Chloropyridin-2-yl)-N’-[(1S,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide-d6 or Edoxaban Impurity H-d6 is the labelled analogue of N-(5-Chloropyridin-2-yl)-N’-[(1S,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide (C380745) which is an impurity of Edoxaban (E555520). Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. Edoxaban Impurity H serves as a useful pharmaceutical standard.
References: Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010); Yoshino, T., et al.: Preparation of stereoisomers of N1-(5-chloropyridin-2-yl)-N2-[(1S, 2R, 4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide as pharmaceutical standards and as drugs for treating thrombosis, US Patent 20120053349, Mar 1, 2012;
Dangerous Goods Info: NA

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