6-Chloropyridine-2-carboxylic Acid

Catalogue number: C380615
Chemical name: 6-Chloropyridine-2-carboxylic Acid
Synonyms: 6-Chloropicolinic Acid; 6-Chloro-2-pyridinecarboxylic Acid; 2-Chloropyridine-6-carboxylic Acid; NSC 51587
CAS Number: 4684-94-0
Possible CAS #: NA
Molecular form.: C₆H₄ClNO₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 157.55
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Intermediates
Boiling Point: No Data Available
Applications: 6-Chloropyridine-2-carboxylic Acid is an intermediate of Sorafenib b(S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
Dangerous Goods Info: NA
References: Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003); Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004); Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004); Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)
Peer Review Product Citations:

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