Catalogue number: C380165
Chemical name: (3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
Synonyms: THIQ
CAS Number: 312637-48-2
Possible CAS #: NA
Molecular form.: C₃₃H₄₁ClN₆O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 589.17
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide, is a selective melanocortin 4 receptor. It is shown that this MC4R agonist, inhibit parasympathetic preganglionic neurons in the brainstem,regulating sympathetic and parasympathetic preganglionic neurons and are involved in regulation of insulin levels and in development of obesity-induced hypertension.
Dangerous Goods Info: NA
References: Sohn, J.W., et al.: Cell. 152, 612 (2013); Martin, et al.: Eur. J. Pharmacol., 71, 454, (2002);
Peer Review Product Citations:

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