1-(3-Chlorophenyl)piperazine

Catalogue number: C379590
Chemical name: 1-(3-Chlorophenyl)piperazine
Synonyms: 1-(m-Chlorophenyl)piperazine; 4-(3-Chlorophenyl)piperazine; N-(3-Chlorophenyl)piperazine; N-(m-Chlorophenyl)piperazine; NSC 49307; mCPP;
CAS Number: 6640-24-0
Possible CAS #: NA
Molecular form.: C₁₀H₁₃ClN₂
Appearance: Colourless Oil
Melting Point: N/A
Mol. Weight: 196.68
Storage: -20˚C Freezer, Under Inert Atmosphere
Solubility: Methanol
Stability: No Data Available
Category: Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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