(E)-2-[(2-Chlorophenyl)methylene]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester

Catalogue number: C378120
Chemical name: (E)-2-[(2-Chlorophenyl)methylene]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₃H₂₀ClNO₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 441.86
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: (E)-2-[(2-Chlorophenyl)methylene]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester is an impurity in the synthesis of Amlodipine Besilate (A633500); a dihydropyridine calcium channel blocker which is also used as an antianginal and antihypertensive.
Dangerous Goods Info: NA
References: Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996)
Peer Review Product Citations:

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