2-Chloro-5-nitro-N-4-phenylbenzamide

Catalogue number: C374050
Chemical name: 2-Chloro-5-nitro-N-4-phenylbenzamide
Synonyms: GW9662
CAS Number: 22978-25-2
Possible CAS #: NA
Molecular form.: C₁₃H₉ClN₂O₃
Appearance: White to Off-White Solid
Melting Point: 157-159°C
Mol. Weight: 276.68
Storage: Refrigerator
Solubility: DMSO (Slightly),Methanol (Slightly)
Stability: No Data Available
Category: Inhibitors
Boiling Point: No Data Available
Applications: A cell-permeable, selective and irreversible PPARγ antagonist (IC50 = 3.3 nM, 32 nM, and 2 µM for PPARγ, PPARα, and PPARδ, respectively). Reported to covalently modify a cysteine residue in the binding site of PPAR. At a concentration of 10 µM, also acts as an agonist of human pregnane X receptor (PXR) and farnesoid X receptor (FXR). Does not activate liver X receptor-a (LXRa), retinoic acid receptor (RAR), retinoid X receptor-a (RXRa) and thyroid receptors a and b (TRa and TRb
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
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50mg $235.00
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5mg $50.00
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25mg $140.00
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100mg $445.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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