4-Chloro-3-fluoroaniline

Catalogue number: C367100
Chemical name: 4-Chloro-3-fluoroaniline
Synonyms: 4-Chloro-3-fluoro-aniline; 3-Fluoro-4-chloroaniline; 3-Fluoro-4-chlorobenzenamine; 4-Chloro-3-fluorobenzenamine; 4-Chloro-3-fluoro-benzeneamine; 4-Chloro-3-fluorophenylamine
CAS Number: 367-22-6
Possible CAS #: NA
Molecular form.: C₆H₅ClFN
Appearance: Off-White Solid
Melting Point: No data available
Mol. Weight: 145.56
Storage: Refrigerator, under inert atmosphere
Solubility: Chloroform, DMSO, Methanol
Stability: No Data Available
Category: Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 4-Chloro-3-fluoroaniline is used in the synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate; a key intermediate towards phosphoindole inhibitors of HIV non-nucleoside reverse transcriptase. 4-Chloro-3-fluoroaniline is also used in the synthesis of 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib (D289540) which is an impurity of the tyrosine kinase inhibitor Gefitinib (G304000).
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References:
Peer Review Product Citations:

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