4-Chloro Kynurenine-13C2,15N

Catalogue number: C366942
Chemical name: 4-Chloro Kynurenine-13C2,15N
Synonyms: α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid-13C2,15N; (+/-)-α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid-13C2,15N; 4-Cl-KYN-13C2,15N; (+/-)-AV-101-13C2,15N;
CAS Number: 1391051-72-1
Possible CAS #: NA
Molecular form.: C₈¹³C₂H₁₁ClN¹⁵NO₃
Appearance: Pale Yellow Solid
Melting Point: >195°C (dec.)
Mol. Weight: 245.64
Storage: Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
Solubility: Aqueous Acid (Slightly)
Stability: No Data Available
Category: Amines, Aromatics, Drug Analogues, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 7-Cl-kynurenic acid (7-Cl-KYNA) is a potent, selective antagonist of the NMDA/glycine receptor but penetrates poorly through the blood-brain barrier.  Its prodrug, L-4-Cl-kynurenine (4-Cl-KYN), readily enters the brain from the circulation and provides antiexcitotoxic neuroprotection after systemic application.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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