4-Chloro Kynurenine

Catalogue number: C366940
Chemical name: 4-Chloro Kynurenine
Synonyms: α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid; (+/-)-α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid; 4-Cl-KYN; (+/-)-AV-101;
CAS Number: 75802-84-5
Possible CAS #: NA
Molecular form.: C₁₀H₁₁ClN₂O₃
Appearance: Yellow Solid
Melting Point: >188°C (dec.)
Mol. Weight: 242.66
Storage: Refrigerator
Solubility: Aqueous Acid, DMSO (Sparingly)
Stability: No Data Available
Category: Amines, Aromatics, Drug Analogues, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 7-Cl-kynurenic acid (7-Cl-KYNA) is a potent, selective antagonist of the NMDA/glycine receptor but penetrates poorly through the blood-brain barrier.  Its prodrug, L-4-Cl-kynurenine (4-Cl-KYN), readily enters the brain from the circulation and provides antiexcitotoxic neuroprotection after systemic application.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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