Catalogue number: C366485
Chemical name: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[2-((1-Oxyl-2,2,5,5-tetramethylpyrroline-3-yl)carbamido)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine
Synonyms: Demethylsulfonyl Lapatinib 1-Oxyl-2,2,5,5-tetramethyl-Æ3-pyrroline deriv;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₃₇H₃₇ClFN₆O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 684.18
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
Boiling Point: No Data Available
Applications: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[2-((1-Oxyl-2,2,5,5-tetramethylpyrroline-3-yl)carbamido)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine is an analog of Lapatinib Ditosylate (L175800) which acts as a reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic.
References: Kim, T.E., et al.: Drugs, 6, 886 (2003), Wood, E.R., et al.: Cancer Res., 64, 6652 (2004), Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2005),
Dangerous Goods Info: NA

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