Catalogue number: C364235
Chemical name: N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine
CAS Number: 1384516-10-2
Possible CAS #: NA
Molecular form.: C₁₂H₁₁ClN₂O₂S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 282.75
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.
Dangerous Goods Info: NA
References: Kojetin, D. et al.: ACS Chem. Biol., 6, 131 (2011); Grant, D. et al.: ACS Chem. Biol., 5, 925 (2010)
Peer Review Product Citations:

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