Catalogue number: C363785
Chemical name: (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Synonyms: (2R)-1-(2-Chloroacetyl)-2-pyrrolidinecarbonitrile;
CAS Number: 565452-98-4
Possible CAS #: NA
Molecular form.: C₇H₉ClN₂O
Appearance: Pale Yellow Solid
Melting Point: 64-67°C
Mol. Weight: 172.61
Storage: -20°C Freezer
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Heterocycles, Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.
Dangerous Goods Info: NA
References: Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008); Villhauer, E. B., et al.: J. Med. Chem., 46, 2774 (2003);
Peer Review Product Citations:

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