CHIR 124

Catalogue number: C292085
Chemical name: CHIR 124
Synonyms: 4-[((3S)-1-Azabicyclo[2.2.2]oct-3-yl)amino]-3-(1H-benzimidazol-2-yl)-6-chloroquinolin-2(1H)-one; 4-[(3S)-1-Azabicyclo[2.2.2]oct-3-ylamino]-3-(1H-benzimidazol-2-yl)-6-chloro-2(1H)-quinolinone;
CAS Number: 405168-58-3
Possible CAS #: NA
Molecular form.: C₂₃H₂₂ClN₅O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 419.91
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: CHIR 124 is a cell-permeable molecule with a quinolone-based structure. It inhibits checkpoint kinase 1 (Chk1) which regulates S and G2-M cekk cycle checkpoints in response to DNA damage. Application towards inhibition of tumor cell growth.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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