Cerivastatin lactone

Catalogue number: C277005
Chemical name: Cerivastatin lactone
Synonyms: [4R-[4α,6β(E)]]-6-[2-[4-(4-Fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one; (4R,6S)-6-((E)-2-(4-(4-Fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one; (4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one
CAS Number: 158878-47-8
Possible CAS #: NA
Molecular form.: C₂₆H₃₂FNO₄
Appearance: White Solid
Melting Point: 104-106°C
Mol. Weight: 441.53
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Cerivastatin lactone is a metabolite of a competitive inhibitor of HMG-CoA reductase, Cerivastatin (C277000). Cerivastatin lactone shows inhibitory effects on CYP3A4/5 activity.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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