Catalogue number: C228800
Chemical name: CDPPB
Synonyms: 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
CAS Number: 781652-57-1
Possible CAS #: NA
Molecular form.: C₂₃H₁₆N₄O
Appearance: White Solid
Melting Point: 210-212°C
Mol. Weight: 364.4
Storage: Refrigerator
Solubility: DMSO, Ethyl Acetate
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: CDPPB is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that CDPPB suppresses the increase of LDH release and caspase-3 activation induced by traumatic neuronal injury.
Dangerous Goods Info: NA
References: Chen, T. et al.: Neurochem. Res., 37, 983 (2012); Rodriguez, A. et al.: Bioorg. Med. Chem. Lett., 22, 7388 (2012); Gregory, K. et al.: Mol. Pharmacol., 82, 860 (2012)
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $90.00
25mg $300.00
  Pack size Price(USD)
10mg $130.00
50mg $575.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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