Apoptosis, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
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CDDO Imidozolide (CDDO-Im) is a synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Studies show that CDDO-Im is highly active in suppressing cellular proliferation of human leukemia and breast cancer cell lines as well as being an effective therapeutic agent in the treatment of other types of cancers.
Dangerous Goods Info:
Hughes, D.T. et al.: Cancer Invest., 26, 118 (2008); Place, A.E. et al.: Clin. Cancer Res., 9, 2798 (2003); Samudio, I. et al.: J. Biol. Chem., 280, 36273 (2005);