CDDO Imidazolide

Catalogue number: C228090
Chemical name: CDDO Imidazolide
Synonyms: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid imidazolide; CDDO-Im; RTA 403; TP 235;
CAS Number: 443104-02-7
Possible CAS #: NA
Molecular form.: C₃₄H₄₃N₃O₃
Appearance: Pale Yellow to Tan Solid
Melting Point: 179-192°C (dec.)
Mol. Weight: 541.72
Storage: Amber Vial, -20˚C Freezer, Under Inert Atmosphere
Solubility: Chloroform, Methanol (Sparingly)
Stability: No Data Available
Category: Apoptosis, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Boiling Point: No Data Available
Applications: CDDO Imidozolide (CDDO-Im) is a synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Studies show that CDDO-Im is highly active in suppressing cellular proliferation of human leukemia and breast cancer cell lines as well as being an effective therapeutic agent in the treatment of other types of cancers.
Dangerous Goods Info: NA
References: Hughes, D.T. et al.: Cancer Invest., 26, 118 (2008); Place, A.E. et al.: Clin. Cancer Res., 9, 2798 (2003); Samudio, I. et al.: J. Biol. Chem., 280, 36273 (2005);
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $350.00
  Pack size Price(USD)
10mg $2800.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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