Catalogue number: C183462
Chemical name: Carfilzomib-d8
Synonyms: (αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide-d8; (αS)-α-[(4-Morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-phenylalaninamide-d8; PR 171-d8;
CAS Number: 1537187-53-3
Possible CAS #: Unlabeled: 868540-17-4
Molecular form.: C₄₀H₄₉D₈N₅O₇
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 727.96
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Isotope Labeled CompoundPharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Carfilzomib-d8, is the labeled analogue of Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
Dangerous Goods Info: NA
References: Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);
Peer Review Product Citations:

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