9-(2-Carboxyphenyl)-2,7-dimethyl-3,6-bis(ethylamino)xanthylium

Catalogue number: C178520
Chemical name: 9-(2-Carboxyphenyl)-2,7-dimethyl-3,6-bis(ethylamino)xanthylium
Synonyms: Rhodamine 19; Rhodamine 19 Zwitterion; Rhodamine 575; o-[6-(Ethylamino)-3-(ethylimino)-2,7-dimethyl-3H-xanthen-9-yl]-benzoic Acid; 9-(2-Carboxyphenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium Inner Salt;
CAS Number: 25152-49-2
Possible CAS #: NA
Molecular form.: C₂₆H₂₆N₂O₃
Appearance: Purple Solid
Melting Point: No Data Available
Mol. Weight: 414.5
Storage: No Data Available
Solubility: Hot Methanol
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: 9-(2-Carboxyphenyl)-2,7-dimethyl-3,6-bis(ethylamino)xanthylium is an intermediate in the synthesis of SkQR1 (S555050), a mitochondria-targeted plastoquinone antioxidant that exhibits neuroprotective effect. Potent Mitochondrial Targeted antioxidant protecting against the anti-cancer treatment related to oxidative stress (1). Depicted positive effects on rat memory. (2) SkQRl is the substrate of multidrug resistance pump P-glycoproten (Pgp 170) and selectively protects Pgp 170-negative cells against oxidative stress (3)
Dangerous Goods Info: NA
References: PMID: 19995561
PMID: 26071778
PMID: 25496313
Peer Review Product Citations:

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