Catalogue number: C175175
Chemical name: Canadine
Synonyms: 5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine; 9-Deoxy-16,17-dihydroberberine; 9,10-Dimethoxy-2,3-(methylenedioxy)berbine; (±)-Canadine; (±)-Tetrahydroberberine; Tetrahydroberberine,; NSC 36351; NSC 94918; Tetrahydroberberine; Tetrahydroumbellatine; Xanthopuccine; dl-Canadine; dl-Tetrahydroberberine;
CAS Number: 522-97-4
Possible CAS #: NA
Molecular form.: C₂₀H₂₁NO₄
Appearance: Greenish Yellow Solid
Melting Point: >167°C (dec.)
Mol. Weight: 339.39
Storage: Refrigerator
Solubility: Chloroform, Methanol
Stability: No Data Available
Category: Aromatics, Heterocycles, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.
Dangerous Goods Info: NA
References: Duchowicz, P., et al.: Bioorg. Med. Chem., 14, 5876 (2006), Sun., et al.: Br. J. Pharmcol., 158, 1302 (2009), Deeb, O., et al.: Chem. Biol. Drug Des., 76, 255 (2010),
Peer Review Product Citations:

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2mg $55.00
10mg $140.00
50mg $615.00
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5mg $110.00
25mg $325.00
100mg $1120.00
Exact Weight Packaging ($75(USD) / Vial)
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