Calcein AM

Catalogue number: C125400
Chemical name: Calcein AM
Synonyms: N,N’-[[3’,6’-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9’-[9H]xanthene]-2’,7’-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1’-Bis[(acetyloxy) methyl] Ester; Calcein Acetoxymethyl Ester; NSC 689290;
CAS Number: 148504-34-1
Possible CAS #: NA
Molecular form.: C₄₆H₄₆N₂O₂₃
Appearance: Off-White Solid
Melting Point: >65°C (dec.)
Mol. Weight: 994.86
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO, Methanol (Sparingly)
Stability: No Data Available
Category: Amines, Aromatics, Fluorescent Labels & Indicators, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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50µg $95.00
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1mg $265.00
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.5mg $150.00
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5mg $1200.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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