tert-Butyl ((S)-4-Methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate

Catalogue number: B809210
Chemical name: tert-Butyl ((S)-4-Methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate
Synonyms: N-[(1S)-3-Methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]carbamic Acid 1,1-Dimethylethyl Ester; [(1S)-3-Methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]carbamic Acid 1,1-Dimethylethyl Ester; (2R)-2-[(2S)-2-(tert-Butoxycarbonylamino)-4-methylpentanoyl]-2-methyloxirane
CAS Number: 247068-82-2
Possible CAS #: Deleted:1334608-29-5
Molecular form.: C₁₄H₂₅NO₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 271.35
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: tert-Butyl ((S)-4-Methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate is an intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
References: Wang, P., et al.: Process for preparation of carfilzomib, China Patent 2015010436, Jan 29, 2015; Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012)
Dangerous Goods Info: NA

Order Product

  Pack size Price(USD)
1mg $75.00
50mg $195.00
250mg $575.00
  Pack size Price(USD)
10mg $110.00
100mg $325.00
500mg $950.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Available in 2-3 weeks

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Search By Category

Search By Category View products by category
Translate »