(1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid

Catalogue number: B694100
Chemical name: (1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid
Synonyms: (1R,​3S,​4S)​-2-​Azabicyclo[2.2.1]​heptane-​2,​3-​dicarboxylic Acid 2-​(1,​1-Dimethylethyl) Ester; (1R,​3S,​4S)​-N-Boc-2-​Azabicyclo[2.2.1]​heptane-​2,​3-​dicarboxylic Acid
CAS Number: 291775-59-2
Possible CAS #: NA
Molecular form.: C₁₂H₁₉NO₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 241.28
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Heterocycles, Miscellaneous Reagents
Boiling Point: No Data Available
Applications: (1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid is a building block in the synthesis of Ledipasvir, a potent, once-​daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References: Link, J., et al.: J. Med. Chem., 57, 2033(2014); Al-Hornai, R;, et al.:Eur. J. Med. Chem., 54, 771 (2012)
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
250mg $85.00
5g $675.00
  Pack size Price(USD)
1g $175.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Available in 2-3 weeks

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Search By Category

Search By Category View products by category
Translate »