(1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol

Catalogue number: B692540
Chemical name: (1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol
Synonyms: trans-4-[[2-(Butylamino)-5-[5-(4-morpholinylmethyl)-2-pyridinyl]-4-pyrimidinyl]amino]cyclohexanol; UNC2250
CAS Number: 1493694-70-4
Possible CAS #: NA
Molecular form.: C₂₄H₃₆N₆O₂
Appearance: Light Yellow Solid
Melting Point: 207-210ºC
Mol. Weight: 440.58
Storage: Refrigerator, under inert atmosphere
Solubility: Chloroform (Slightly, Heated), Ethyl Acetate (Slightly, Heated), Methanol (Sligh
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol inhibits steady-state phosphorylation of endogenous Mer and blocks ligand-stimulated activation of a chimeric EGFR-Mer protein. (1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol also decreases colony-forming potential in rhabdoid and NSCLC tumor cells.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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