tert-Butoxycarbonyl-D-proline

Catalogue number: B692535
Chemical name: tert-Butoxycarbonyl-D-proline
Synonyms: (2R)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester; (R)-1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester; (2R)-1-tert-Butoxycarbonylpyrrolidine-2-carboxylic acid; (R)-1-(tert-Butyloxycarbonyl)pyrrolidine-2-carboxylic acid; (R)-1-tert-Butoxycarbonylpyrrolidine-2-carboxylic acid; (R)-2-Carboxypyrrolidine-1-carboxylic acid tert-butyl ester; (R)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester; 1-tert-Butoxycarbonyl-D-proline; 1-tert-Butyl (R)-pyrrolidine-1,2-dicarboxylate; N-(tert-Butoxycarbonyl)-(R)-proline; N-BOC-D-proline; N-tert-Butoxycarbonyl-D-proline; NSC 334360
CAS Number: 37784-17-1
Possible CAS #: NA
Molecular form.: C₁₀H₁₇NO₄
Appearance: Off-White Solid
Melting Point: 131-135ºC
Mol. Weight: 215.25
Storage: Refrigerator
Solubility: Chloroform (Slightly), DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Chiral Reagents, Miscellaneous Reagents
Boiling Point: No Data Available
Applications: tert-Butoxycarbonyl-D-proline is Boc protected D-proline (P755990). It is used to prepare trichostatin A and trapoxin B analogs as histone deacetylase inhibitors. It is also used to prepare potent and selective nonpeptide inhibitors of caspases 3 and 7.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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