O-tert-Butyl-dimethylsilyl Curcumin

Catalogue number: B691020
Chemical name: O-tert-Butyl-dimethylsilyl Curcumin
Synonyms: (1E,4Z,6E)-7-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one
CAS Number: 911292-36-9
Possible CAS #: NA
Molecular form.: C₂₇H₃₄O₆Si
Appearance: Yellow Solid
Melting Point: >129°C (dec.)
Mol. Weight: 482.64
Storage: Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Protected Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
100mg $140.00
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  Pack size Price(USD)
1g $1120.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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