4-Bromo-1,1,2-trifluoro-1-butene is used as a reagent in the synthesis of a series of N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives as potent caspase-3 and caspase-7 inhibitors known to be downstream enzymes critical in the execution of apoptosis.
Dangerous Goods Info:
Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
Podichetty, A.K., et al.: Bioorg. Med. Chem., 17, 2680 (2009)