Catalogue number: B688280
Chemical name: 3’-Bromo-4’-methylacetophenone
Synonyms: 1-(3-Bromo-4-methylphenyl)ethanone; 3-Bromo-4-methylacetophenone
CAS Number: 40180-80-1
Possible CAS #: NA
Molecular form.: C₉H₉BrO
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 213.07
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: 3’-Bromo-4’-methylacetophenone is used as a starting material in the synthesis of mansonone E which is used to make mansonone E dervivatives. These derivatives are potent inhibitors of topoisomerase II (Topo II) and topoisomerase I (Topo I) and are also potent antitumor agents. 3’-Bromo-4’-methylacetophenone is also used as a reagent in the synthesis of BAF312, Siponimod which has been tested in the treatment of patients suffering from relapsing-remitting multiple sclerosis.
Dangerous Goods Info: NA
References: Fang, X., et al.: J. Chem. Res., 38, 137 (2014); Huang, Z., et al.: Eur. J. Med. Chem., 68, 58 (2013); Pan, S., et al.: ACS Med. Chem. Lett., 4, 333 (2013)
Peer Review Product Citations:

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