Bromoconduritol (Mixture of Isomers)

Catalogue number: B682500
Chemical name: Bromoconduritol (Mixture of Isomers)
Synonyms: 6-Bromo-3,4,5-trihydroxy Cyclohex-1-ene; 6-Bromo-4-cyclohexene-1,2,3-triol;
CAS Number: 42014-74-4
Possible CAS #: NA
Molecular form.: C₆H₉O₃Br
Appearance: White to Off-White Solid
Melting Point: 115-118°C
Mol. Weight: 209.04
Storage: No Data Available
Solubility: Water
Stability: No Data Available
Category: Inhibitors, Glycosidase Inhibitors,
Boiling Point: No Data Available
Applications: Bromoconduritol selectively inhibits mammalian alpha-glucosidase 2 (Glc2/Glc1 glucosidase in the glycoprotein processing pathway), yeast alpha-glucosidase, and some beta-glucosidases. It does not inhibit mammalian alpha-glucosidase 1 (Glc3-glucosidase) or mammalian Golgi mannosidase 1 (alpha-1,2-specific) in the glycoprotein processing pathway; the formation of lipid-linked oligosaccharide precursor (dolichol pyrphosphate oligosaccharide) and the transfer of lipid-linked oligosaccharide to proteins. Preparations in ice-cold H2O should be used immediately. The half-time for decomposition of bromoconduritol A (debromination) is 16 min (H2O, pH 7.3, 37oC). Under similar conditions, the half-life of bromoconduritol B is 2 mins. Working concentration for the inhibition of glycoprotein
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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