Catalogue number: B682190
Chemical name: 3-Bromo-6-chloro-1H-pyrazolo[3,4-d]pyrimidine
CAS Number: 944903-06-4
Possible CAS #: NA
Molecular form.: C₅H₂BrClN₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 233.45
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Nucleotides, Bases & Related Reagents, Sulfur & Selenium Compounds,
Boiling Point: No Data Available
Applications: Pyrazolo[3,4-d]pyrimidines have a close structural resemblance to the substrates for the enzyme xanthine oxidase, hypoxanthine (6-hydroxypurine) and xanthine (2,6-dihydroxypurine). These compounds are capable of binding to the enzyme and strongly inhibit its activity. They have been studied for their role in the treatment and prophylaxis of hyperuricemia in human patients as well as potential anti-tumor agents.
Dangerous Goods Info: NA
References: Massey, V., et al.: J. Biol. Chem., 245, 2837 (1970), Escribano, J., et al.: Biochem. J., 254, 829 (1988_,,,,,13) Van Hoorn, D; Eur J Pharmacol 2002, 451, 111,,14) Tamta, H; J Enzyme Inhibition Med Chem 2005, 20, 317
Peer Review Product Citations:

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