Catalogue number: B680510
Chemical name: 8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione
Synonyms: 1-[(4-Methylquinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-bromoxanthine
CAS Number: 853029-57-9
Possible CAS #: NA
Molecular form.: C₂₀H₁₇BrN₆O₂
Appearance: Pale Yellow Solid
Melting Point: >255°C (dec.)
Mol. Weight: 453.29
Storage: Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated)
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: 8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione is an intermediate used to prepare selective inhibitors of dipeptidyl peptidase 4 (DPP4) for potential use in the treatment of type 2 diabetes.
Dangerous Goods Info: NA
References: Sutton, J., et al.: Bioorg. Med. Chem. Lett., 22, 1464 (2012); Lai, Z., et al.: Eur. J. Med. Chem., 83, 547 (2014)
Peer Review Product Citations:

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