Catalogue number: B676632
Chemical name: (-)-trans-anti-N2-BPDE-dG-d8
Synonyms: [7S-(7α,8β,9β,10α)]-2’-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine-d8; Benzo[a]pyrene, guanosine deriv.-d8; (-)-trans-anti-7,8,9-Trihydroxy-10-(2’-deoxyguanosin-2-yl)benzo[a]pyrene-d8
CAS Number: NA
Possible CAS #: Unlabelled: 85026-87-5
Molecular form.: C₃₀H₁₉D₈N₅O₇
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 577.61
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Isotope Labelled Compounds, Mutagenesis Research Chemicals, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Isotope labelled (-)-trans-anti-N2-BPDE-dG-d8 is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair.
Dangerous Goods Info: NA
References: Skosareva, L. et al.: DNA Repair., 11, 367 (2012); Minero, A. et al.: FEBS J. et al.: 279, 3965 (2012); Hoare, S. et al.: Biochem., 39, 12252 (2000); Subach, O. et al.: Biochem., 45, 6142 (2006);
Peer Review Product Citations:

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