(1S,2R)-Bortezomib

Catalogue number: B675710
Chemical name: (1S,2R)-Bortezomib
Synonyms: B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid
CAS Number: 1132709-16-0
Possible CAS #: NA
Molecular form.: C₁₉H₂₅BN₄O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 384.24
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Chiral Reagents, Boron Derivatives, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: (1S,3R)-Bortezomib is an diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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