BMS 599626-d4

Catalogue number: B596302
Chemical name: BMS 599626-d4
Synonyms: N-[4-[[1-[(3-Fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamic Acid (3S)-3-Morpholinylmethyl-d4 Ester; AC 480-d4;
CAS Number: 1330172-72-9
Possible CAS #: 714971-09-2-unlabelled
Molecular form.: C₂₇H₂₃D₄FN₈O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 534.58
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemical
Boiling Point: No Data Available
Applications: It is a highly selective and potent inhibitor of HER1 and HER2 kinases and inhibits tumor cell proliferation through modulation of receptor signaling. BMS-599626 inhibits HER1/HER2 receptor heterodimerization and provides an additional mechanism of inhibiting tumors in which receptor coexpression and heterodimerization play a major role in driving tumor growth.
Dangerous Goods Info: NA
References: Wiseman, L., et al.: Eur. J. Cancer, 29A, 2256 (1993), Wittman, M., et al.: J. Med. Chem., 48, 5639 (2005), Allen, G., et al.: Cancer Res., 67, 1155 (2007),
Peer Review Product Citations:

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5mg $9750.00
  Pack size Price(USD)
Exact Weight Packaging ($75(USD) / Vial)
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