(R)-(+)-Blebbistatin O-Benzoate

Catalogue number: B592530
Chemical name: (R)-(+)-Blebbistatin O-Benzoate
Synonyms: (R)-3a-(Benzoyloxy)-1,2,3,3a-tetrahydro-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one;
CAS Number: 1217635-67-0
Possible CAS #: NA
Molecular form.: C₂₅H₂₀N₂O₃
Appearance: Orange Solid
Melting Point: 157-159°C
Mol. Weight: 396.44
Storage: Refrigerator
Solubility: Chloroform, Methanol
Stability: No Data Available
Category: Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: (R)-(+)-Blebbistatin O-Benzoate is a derivative of Blebbistatin (B592495). (R)-(+)-Blebbistatin is a 1-phenyl-2-pyrrolidinone derivative and a selective inhibitor of non-muscle myosin II (1, 2, 3). It blocks cell blebbing rapidly and reversibly and also disrupts directed cell migration and cytokinesis in vertebrate cell. (R)-(+)-Blebbistatin can also inhibit contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. (R)-(+)-Blebbistatin is suitable as a negative control for (S)-(-)-Blebblastatin.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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