Catalogue number: B591452
Chemical name: Bitopertin-d8
Synonyms: [4-[3-Fluoro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl-d8][5-(methylsulfonyl)-2-[(1S)-2,2,2-trifluoro-1-methylethoxy]phenyl]methanone; (S)-[4-(3-Fluoro-5-trifluoromethyl- pyridin-2-yl)(piperazin-d8)-1-yl][5-(methanesulfonyl)-2-(2,2,2-trifluoro-1-methylethoxy)phenyl]methanone; R 1678-d8; RG 1678-d8; Ro 4917939-d8;
CAS Number: NA
Possible CAS #: unlabelled: 845614-11-1
Molecular form.: C₂₁H₁₂D₈F₇N₃O₄S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 551.5
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: Labelled Bitopertin (B591450). Bitopertin is a potent and noncompetitive glycine reuptake inhibitor (GRI). Bitopertin is an investigational agent for the treatment of schizophrenia.
Dangerous Goods Info: NA
References: Donzanti, B., et al.: Life Sci., 43, 913 (1988); Brown, A., et al.: Bioorg. Med. Chem. Lett., 11, 2007 (2001), Caulfield, W., et al.: Med. Chem., 44, 2679 (2001), Harsing, L., et al.: Curr. Med. Chem., 13, 1017 (2006),
Peer Review Product Citations:

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