N,N-Bis-desethyl, N-Methyl Entacapone

Catalogue number: B415095
Chemical name: N,N-Bis-desethyl, N-Methyl Entacapone
Synonyms: (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methyl-2-propenamide;
CAS Number: 1364322-41-7
Possible CAS #: NA
Molecular form.: C₁₁H₉N₃O₅
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 263.21
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: N,N-Bis-desethyl, N-Methyl Entacapone is an impurity of Entacapone (E558500). The (E)-Isomer of Entacapone which is a polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
Dangerous Goods Info: NA
References: Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),
Peer Review Product Citations:

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