Catalogue number: B387052
Chemical name: Bindarit-d5
Synonyms: 2-Methyl-2-[[1-(phenylmethyl)-1H-indazol-3-yl]methoxy]propanoic Acid-d5; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic Acid-d5; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropionic Acid-d5; AF 2838-d5;
CAS Number: NA
Possible CAS #: Unlabelled: 130641-38-2
Molecular form.: C₁₉H₁₅D₅N₂O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 329.4
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Isotope labelled analogue of Bindarit (B387050), a compound that shows anti-inflammatory activity due to a selective inhibition of a subfamily of inflammatory chemokines. Bindarit is a also protein antidenaturant agent. Bindarit modulates the NFkB pathway and has been shown to reduce secondary phase of adjuvant arthritis in rats.
Dangerous Goods Info: NA
References: Mora, E. et al.: Call Cycle, 11, 169 (2012); Cioli, V. et al.: J. Rheumatol., 19, 1735 (1992); Guglielmotti, A. et al.: Inflam. Res., 51, 252 (2002); Grassia, G. et al.: Cardio. Res., 84, 485 (2009);
Peer Review Product Citations:

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