Berberine Hydrochloride

Catalogue number: B318150
Chemical name: Berberine Hydrochloride
Synonyms: 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Chloride; Berberine Chloride; 7,8,13,13a-Tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)berbinium Chloride; Berberine Hydrochloride; NSC 646666;
CAS Number: 633-65-8
Possible CAS #: NA
Molecular form.: C₂₀H₁₈ClNO₄
Appearance: Pale Yellow to Yellow Solid
Melting Point: >160°C (dec.)
Mol. Weight: 371.84
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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