Catalogue number: B287815
Chemical name: N-(Benzyloxycarbonyl)-D-proline
Synonyms: (2R)-1,2-Pyrrolidinedicarboxylic acid 1-(Phenylmethyl) Ester; (R)-1,2-Pyrrolidinedicarboxylic acid 1-(Phenylmethyl) Ester, ; D-1,2-Pyrrolidinedicarboxylic acid 1-Benzyl Ester; (2R)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid; (Benzyloxycarbonyl)-D-proline; (R)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid; (R)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid; 1-(Benzyloxycarbonyl)-D-proline; D-Cbz-Proline; N-(Benzyloxycarbonyl)-(R)-proline; N-Carbobenzyloxy-D-proline; Z-D-PRO-OH
CAS Number: 6404-31-5
Possible CAS #: NA
Molecular form.: C₁₃H₁₅NO₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 249.26
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Amino Acids & Derivatives, Aromatics, Chiral Reagents
Boiling Point: No Data Available
Applications: N-(Benzyloxycarbonyl)-D-proline is an an N-Cbz-protected form of D-proline (P755990). It is used to prepare trichostatin A and trapoxin B analogs as histone deacetylase inhibitors. It is also used to prepare potent and selective nonpeptide inhibitors of caspases 3 and 7.
Dangerous Goods Info: NA
References: Jung, M., et al.: Bioorg. Med. Chem. Lett., 7, 1655 (1997); Lee, D., et al.: J. Med. Chem,, 44, 2015 (2001)
Peer Review Product Citations:

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