BAY 87-2243-d8

Catalogue number: B119072
Chemical name: BAY 87-2243-d8
Synonyms: 1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]-piperazine-d8
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₆H₁₈D₈F₃N₇O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 533.57
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Isotope labelled BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation. It is found to inhibit HIF-1α and HIF-2α protein accumulation under hypoxic conditions in non-small cell lung cancer cell line H460. It inhibits mitochondrial complex I activity and therefore may be used in antitumor treatment to overcome chemo- and radiotherapy- resistance of hypoxic tumors.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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.5mg $250.00
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