Bardoxolone

Catalogue number: B118660
Chemical name: Bardoxolone
Synonyms: CDDO; RTA 401; 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid;
CAS Number: 218600-44-3
Possible CAS #: NA
Molecular form.: C₃₁H₄₁O₄
Appearance: Light Brown Solid
Melting Point: >280ºC (dec.)
Mol. Weight: 491.66
Storage: -20˚C Freezer
Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Bardoxolone is a synthetic oleanane triterpenoid that exerts multifunctional activities in the control of cellular growth and differentiation. Bardoxolone is capable of activating the transcription factor peroxisome proliferator activator receptor-γ (PPARγ), its apoptotic effects in malignant cells have been shown to occur independently of PPARγ. Bardoxolone was developed as an potential drug for the improvement of hyperglycemia, proteinuria, glomerulus structure, serum creatine, which may in turn be beneficial to treat diabetic kidney diseases, cancer and thromboembolic events.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $50.00
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10mg $350.00
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50mg $900.00
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  Pack size Price(USD)
5mg $195.00
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25mg $575.00
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100mg $1120.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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