Atrasentan Hydrochloride

Catalogue number: A793930
Chemical name: Atrasentan Hydrochloride
Synonyms: (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic Acid Hydrochloride; [2R-(2α,3β,4α)]-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic Acid Monohydrochloride; A 147627.1; Abbott 147627;
CAS Number: 195733-43-8
Possible CAS #: 173937-91-2-free acid
Molecular form.: C₂₉H₃₉ClN₂O₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 547.08
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Atrasentan, a selective antagonist of the endothelin-A (ETA) receptor, binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.
Dangerous Goods Info: NA
References: Bax, W., et al.: Trends Pharmacol. Sci., 15, 379 (1994); Winn, M., et al.: J. Med. Chem., 39, 1039 (1996); Wu-Wong, J., et al.: J. Pharmacol. Exp. Ther., 281, 791 (1997);
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $225.00
50mg $1375.00
  Pack size Price(USD)
25mg $750.00
100mg $2250.00
Exact Weight Packaging ($75(USD) / Vial)
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