1-β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C

Catalogue number: A764007
Chemical name: 1-β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C
Synonyms: 1-(2-C-Methyl-d3, 13C-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyl-d3, 13C-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; Sofosbuvir Impurity 12-d3, 13C
CAS Number: 1256490-38-6
Possible CAS #: NA
Molecular form.: C₉¹³CH₁₁D₃N₂O₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 262.24
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Carbohydrates & Derivatives, Heterocycles, Impurities, Isotope Labelled Compounds, Nucleotides, Bases & Related Reagents
Boiling Point: No Data Available
Applications: 1-β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C is the labeled analogue of 1-β-D-Arabinofuranosyluracil-2-C-methyl (A764005), an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2’-deoxy-2’-α-fluoro-β-C-methyluridine-5’-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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