Apigenin 7-Glucuronide

Catalogue number: A726505
Chemical name: Apigenin 7-Glucuronide
Synonyms: β-D-5-Hydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-glucopyranosiduronic Acid; Apigenin 7-O-Glucuronide; Apigenin 7-O-β-D-Glucuronide; Apigenin 7-O-β-D-Glucuronopyranoside; Apigenin 7-O-β-Glucuronide; Apigenin 7-Glucuronide; Apigenin 7-β-Glucuronide; Apigenin-7-O-β-D Glucuronoside; Scutellarin A
CAS Number: 29741-09-1
Possible CAS #: NA
Molecular form.: C₂₁H₁₈O₁₁
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 446.36
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Inhibitors, Metabolites & Impurities
Boiling Point: No Data Available
Applications: Apigenin 7-Glucuronide is a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.
Dangerous Goods Info: NA
References: Chaumontet, C., et al.: Carcinogenesis, 15, 2325 (1994), Sato, F., et al.: Biochem. Biophys. Res. Commun., 204, 578 (1994), Kuo, M.L. et al.: Biochem. Biophys. Res. Commun., 212, 767 (1995)
Peer Review Product Citations:

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