Catalogue number: A726500
Chemical name: Apigenin
Synonyms: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4’,5,7-Trihydroxyflavone; Pelargidenon 1449;
CAS Number: 520-36-5
Possible CAS #: NA
Molecular form.: C₁₅H₁₀O₅
Appearance: Yellow Solid
Melting Point: >300°C (dec.)
Mol. Weight: 270.24
Storage: -20°C Freezer
Solubility: DMSO
Stability: No Data Available
Category: Inhibitors
Boiling Point: No Data Available
Applications: Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells. uv(max)ethanol: 269, 340 nm (e= 18,800, 20,900) moderately sol. in hot alcohol
Dangerous Goods Info: NA
References: Chaumontet, C., et al.: Carcinogenesis, 15, 2325 (1994), Sato, F., et al.: Biochem. Biophys. Res. Commun., 204, 578 (1994), Kuo, M.L. et al.: Biochem. Biophys. Res. Commun., 212, 767 (1995)
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
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