Apatinib-d8 Hydrochloride

Catalogue number: A726152
Chemical name: Apatinib-d8 Hydrochloride
Synonyms: N-[4-(1-Cyanocyclopentyl-d8)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide; YN968D1-d8 Hydrochloride;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₄H₁₆D₈ClN₅O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 441.98
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
Boiling Point: No Data Available
Applications: Labelled Apatinib (A726150). Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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