Catalogue number: A726115
Chemical name: Apamin
Synonyms: 32,15-(Iminoethaniminopropanodithiomethano)-31H-pyrrolo[2,1-e1][1,2,5,8,11,14,17,20,23,26,29,32,35,38]dithiadodecaazacyclohentetracontine, cyclic peptide deriv.; Apamin (reduced), cyclic (1→11),(3→15)-bis(disulfide); Apamine; L-Cysteinyl-L-asparaginyl-L-cysteinyl-L-lysyl-L-alanyl-L-prolyl-L-α-glutamyl-L-threonyl-L-alanyl-L-leucyl-L-cysteinyl-L-alanyl-L-arginyl-L-arginyl-L-cysteinyl-L-glutaminyl-L-glutaminyl-L-histidinamide cyclic (1→11),(3→15)-bis(disulfide); Ro 23-6721
CAS Number: 24345-16-2
Possible CAS #: NA
Molecular form.: C₇₉H₁₃₁N₃₁O₂₄S₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 2027.34
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Chiral Reagents, Peptides, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Apamin is a toxin found in bee venom. It is a potent blocker of small conductance Ca2+-activated K+ (SK, KCa2) channels that is more effective at SK2 than SK1 and SK3.
References: Maylie, J., et al.; J. Physiol., 554, 255 (2004); Wulff, H., et al.: J. Cardiovasc. Pharmacol., 61, 102 (2013); Triggle, C., et al.: J. Smooth Muscle Res., 39, 249 (2003)
Dangerous Goods Info: NA

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500µg $95.00
5mg $825.00
  Pack size Price(USD)
1mg $175.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Available in 2-3 weeks

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